AKTIVITAS ANTIBAKTERI FRAKSI N-HEKSAN, ETIL ASETAT DAN AIR EKSTRAK ETANOL DAUN SUKUN (ARTOCARPUS ALTILIS) TERHADAP PROPIONIBACTERIUM ACNES
DOI:
https://doi.org/10.30605/biogenerasi.v10i2.6256Keywords:
Artocarpus altilis, antibacterial, Propionibacterium acnesAbstract
The purpose of this study was to determine the antibacterial activity of n-hexane, ethyl acetate and water fractions of breadfruit leaves (Artocarpus altilis) against Propionibacterium acnes. This research method is a laboratory experimental method using a maceration extraction process with 96% ethanol solvent, then the results of the thick extract were diffracted using n-hexane, ethyl acetate and water solvents made with concentrations of 10%, 15% and 20% for each fraction. Furthermore, phytochemical screening and antibacterial activity tests were carried out against Propionibacterium acnes in each fraction. The inhibition zone against Propionibacterium acnes bacteria in the water fraction with a concentration of 10% was 12.47 mm, 15% was 12.88 mm and 20% was 13.37 mm. The inhibition zone of the ethyl acetate fraction with a concentration of 10% was 12.22 mm, a concentration of 15% was 12.62 mm and a concentration of 20% was 13.27. The inhibition zone in the n-hexane fraction with a concentration of 10% was 12.42 mm, 15% was 12.68 mm and 20% was 13.25 mm. It was concluded that for the n-hexane fraction, ethyl acetate and breadfruit leaf water (Artocarpus altilis) have antibacterial activity against Propionibacterium acnes.
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References
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Athaillah, O. :, & Sugesti. (2020). UJI AKTIVITAS ANTIBAKTERI Staphylococcus epidermis MENGGUNAKAN EKSTRAK ETANOL DARI SIMPLISIA KERING BAWANG PUTIH (Allium sativum L.). Jurnal Education and development, vol.8(no.2), 375–380.
Ayuditiawati, M., Azrul Zuniarto, A., Feggy Tanti Tamala, N., & STF YPIB Cirebon, F. (2021). UJI AKTIVITAS ANTIBAKTERI SABUN PADAT EKSTRAK DAUN SUKUN (Artocarpus altilis (Parkins.) Fosberg) TERHADAP BAKTERI Staphylococcus aureus DAN Escherichia coli. Jurnal Farmasi dan Sains, 5(1), 28–43.
Azizah, M., Septy Lingga, L., Rikmasari Sekolah Tinggi Ilmu Farmasi Bhakti Pertiwi Palembang, Y., Selatan, S., Kunci, K., hutan, M., & Penelitian Sains, J. (2020). Uji aktivitas antibakteri kombinasi ekstrak etanol daun seledri (Apium graviolens L.) dan madu hutan terhadap beberapa bakteri penyebab penyakit kulit. Jurnal Penelitian Sains, 22(1), 37–44. https://doi.org/10.26554/jps.v22i1.547
Sifatullah Nur, & Zulkarnain. (2021). Jerawat (Acne vulgaris): Review Penyakit Infeksi Pada Kulit. Prosiding Biologi Achieving the Sustainable Development Goals with Biodiversity in Confronting Climate Change, Vol.7(1). https://doi.org/DOI:https://doi.org/10.24252/psb.v7i1.22212
Lucita, A., & Tensiska. (2021). AKTIVITAS ANTIBAKTERI EKSTRAK DAUN TEH, DAUN SUKUN, DAN DAUN SIRIH TERHADAP Propionbacterium acnes SERTA APLIKASINYA PADA MASKER ANTIJERAWAT. Jurnal Penelitian Pascapanen Pertanian, Volume 18.(2), 105–112.
Maida, S., Ayu, K., Lestari, P., Studi, P., Farmasi, D., & Surabaya, A. F. (2019). AKTIVITAS ANTIBAKTERI AMOKSISILIN TERHADAP BAKTERI GRAM POSITIF DAN BAKTERI GRAM NEGATIF AMOXICIILLIN ANTIBACTERIAL ACTIVITIES ON POSITIVE GRAM BACTERIA AND NEGATIVE GRAM BACTERIA. J. Pijar MIPA, 14(3), 189–191. https://doi.org/10.29303/jpm.1029
Nur Fauziah, S., Evıta Rukaya, B., & Evita Rukaya, B. (2022). UJI AKTIVITAS FRAKSI n-HEXAN DAN ETIL ASETAT EKSTRAK ETANOL DAUN PEPAYA (Carica papaya L.) TERHADAP Propionibacterium acnes. Journal Borneo Science Technology and Health Journal Artikel. www.journalborneo.com
Nuryani, F., Yustinah, Ismiyati, & Ariatmi Nugrahani R. (2022). REKAYASA MODEL LAJU PENGERINGAN PADA PROSES MASERASI DAUN SUKUN (ARTOCARPUS ALTILIS) DENGAN PELARUT ETANOL. Jurnal Konversi, Volume.11(1), 45–50.
Sari Adhani, E., Mulqie, L., & Hazar, S. (2023). STUDI LITERATUR TANAMAN JERUK NIPIS (Citrus aurantifolia Swingle) DAN JERUK LEMON (Citrus limon L.) SEBAGAI ANTIBAKTERI TERHADAP BAKTERI Staphylococcus aureus, Staphylococcus epidermidis Dan Propionibacterium acnes. Bandung Conference Series: Pharmacy, 410–417. https://doi.org/10.29313/bcsp.v3i2.8889
Silviani, Y., & Nirwana, A. P. (2020). AKTIVITAS ANTIBAKTERI EKSTRAK ETIL ASETAT DAUN SUKUN (Artocarpus altilis) METODE PERKOLASI TERHADAP Pseudomonas aeroginusa. Jurnal Kesehatan Kusuma Husada-Januari, Vol.11(1), 7–12. https://doi.org/STIKESNasionalDOI:https://doi.org/10.34035/jk.v11i1.398
Simanjuntak, H. A., & Gurning, K. (2020). UJI AKTIVITAS ANTIBAKTERI DARI SEDIAAN KRIM EKSTRAK ETANOL HERBA TUMBUHAN BALSEM (Polygala paniculata L.) TERHADAP BAKTERI Propionebacterium acnes PENYEBAB JERAWAT. EKSAKTA : Jurnal Penelitian dan Pembelajaran MIPA, 5(2), 133. https://doi.org/10.31604/eksakta.v5i2.133-140
Uswatun Hasanah, R., Sri Rahayu, M., Jend Ahmad Yani Km, J., Harapan, L., & Ilmiah, J. (2023). Uji Efektivitas Antibakteri Ekstrak Etanol Daun Sukun (Artocarpus Altilis) Terhadap Pertumbuhan Bakteri Staphylococcus aureus Antibacterial Effectiveness Test of Breadfruit (Artocarpus Altilis) Leaf Ethanol Extract On The Growth of The Bacteria Of Staphylococcus Aureus.
Zais Farda, N. I. M. (2023). Formulasi Dan Evaluasi Fisik Sediaan Krim Fraksi Etil Asetat Daun Pepaya (Carica Papaya L) Sebagai Anti Jerawat Terhadap Bakteri Propionibacterium Acne (Doctoral Dissertation, Universitas Muhammadiyah Gombong).
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Published
2025-06-28
How to Cite
Hadijah, S., Jangga, Mewar, D., & Rahmadani, H. . (2025). AKTIVITAS ANTIBAKTERI FRAKSI N-HEKSAN, ETIL ASETAT DAN AIR EKSTRAK ETANOL DAUN SUKUN (ARTOCARPUS ALTILIS) TERHADAP PROPIONIBACTERIUM ACNES. Jurnal Biogenerasi, 10(2), 1566–1571. https://doi.org/10.30605/biogenerasi.v10i2.6256
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